RESUMO
With the frequent occurrence of world emergency events, the emergency management of government departments in various countries is facing great challenges. In the context of the COVID-19 pandemic, the shortage of various emergency resources is prominent, and the emergency supplies reserve combined by governments and enterprises is an important guarantee for dealing with emergency management problems. This paper mainly studies the impact of a government sustainability-oriented innovation policy on the production capacity reserve of security emergency enterprises (SEEs), and constructs an evolutionary game model between the local government and SEEs. Then, it focuses on the impact of a reputation mechanism on the government enterprise cooperative reserve. According to the condition of a country, the central government's punishment mechanism is introduced, and the evolutionary and stable strategies of the behavior choices of the local government and SEEs are compared and analyzed. Combined with the evolution degree of emergency events, the numerical simulation analysis is used to deduce and simulate the multi scenario of the example model. The results show that the reputation mechanism can effectively promote the evolution of government and enterprises to the ideal state under various scenarios. When the punishment intensity of the central government is higher than the total benefit of the implementation of the mere formality policy by the local government, it can effectively prevent the omission of the local government. This study provides a new idea for the government to formulate reasonable policies to promote SEEs to reserve production capacity, which is more conducive to government enterprise cooperation to deal with emergency events.
RESUMO
Background: Since its outbreak in late December 2019, the coronavirus disease 2019 (COVID-19) has culminated in a global pandemic, and its causative virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has continued to mutate, with increasing rates of transmission and pathogenicity, having a serious worldwide impact. This study aims to assess the benefits of the health-related quality of life of using N-acetylcysteine(NAC).Methods: In this prospective observational research, 63 confirmed COVID-19 patients who were treated between the ends of January and March 2020 were divided into patients treated with NAC-treatment (32 cases) and non-NAC-treatment groups (31 cases). Patients were followed up at discharge and at 1, 3, and 6 months after discharge. The clinical treatment effects of the two groups were compared, and the St. George’s Respiratory Questionnaire (SGRQ) evaluated patient-reported outcomes.Results: There were strong correlations between SGRQ component scores (0.728, 0.749, 0.850; P < 0.001 for all items) as well as between each SGRQ component score and the total patient score (0.822, 0.958, 0.957; P < 0.001 for all items). In the univariate analysis, the change differences of one month after discharge compared with discharge between two groups patients were statistically significant in the impacts and total scores (753.000, P < 0.001; 644.000, P = 0.042); the change differences of three months after discharge compared with discharge were also significant in the activity, impacts, and total scores (660.500, P = 0.022; 800.000, P < 0.001; 707.000, P = 0.004). In the multivariate analysis, the factors that have statistically significant influence on the unit value of SGRQ total score difference (UVDSGRQ) is NAC treatment (β = 1.954, P < 0.001), disease severity (β = 3.179, P < 0.001), follow-up duration (β = -0.232, P = 0.001), as well as NAC treatment and follow-up duration interaction item (β = -0.436, P = 0.004).Conclusion: Our study shows as the follow-up time increases, the SGRQ total scores of patients treated with NAC decreases significantly faster than those who were treated without NAC. In the treatment of COVID-19 patients, increasing the use of NAC has clinical significance.
Assuntos
COVID-19RESUMO
not available.